{"id":26953,"date":"2024-11-06T12:47:25","date_gmt":"2024-11-06T12:47:25","guid":{"rendered":"https:\/\/prrscontrol.com\/?p=26953"},"modified":"2024-11-06T12:47:25","modified_gmt":"2024-11-06T12:47:25","slug":"prrsv-intradermal-vaccine","status":"publish","type":"post","link":"https:\/\/prrscontrol.com\/zh-hant\/prrsv-intradermal-vaccine\/","title":{"rendered":"\u55ac\u723e\u00b7\u7c73\u862d\u9054\u7b49\u4eba\u57282024\u5e74IPVS\u4e0a\u7684\u51fa\u7248\u7269"},"content":{"rendered":"<h1 style=\"font-weight: 400;\"><strong>\u55ac\u723e\u00b7\u7c73\u862d\u9054\u7b49\u4eba\u57282024\u5e74IPVS\u4e0a\u7684\u51fa\u7248\u7269 <\/strong><\/h1>\n<div>\n<p style=\"font-weight: 400;\">\u55ac\u723e\u00b7\u7c73\u862d\u9054\u7b49\u4eba\u57282024\u5e74IPVS\u4e0a\u7684\u51fa\u7248\u7269\u3002<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<p style=\"text-align: center;\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/RcD_JVlGmZU?si=dJ-4PjKnZUvFWrvT\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<h2>\u5f15\u8a00<\/h2>\n<p>\u75ab\u82d7\u53ef\u4ee5\u6e1b\u5c11\u8c6c\u7e41\u6b96\u8207\u547c\u5438\u7d9c\u5408\u75c7\u75c5\u6bd2\uff08PRRSV\uff09(1,2) \u7684\u81e8\u5e8a\u7d50\u679c\u548c\u751f\u7522\u5f71\u97ff\uff0c\u4e26\u63d0\u4f9b\u5169\u7a2e\u65bd\u6253\u9014\u5f91\uff1a\u808c\u8089\u6ce8\u5c04\uff08IM\uff09\u548c\u76ae\u5167\u6ce8\u5c04\uff08ID\uff09\u3002\u6211\u5011\u7684\u76ee\u6a19\u662f\u8a55\u4f30\u5169\u7a2e\u5546\u696dPRRS MLV\u75ab\u82d7\u7684\u6709\u6548\u6027\u2014\u2014\u4e00\u7a2e\u57fa\u65bcPRRSV1\uff08UNISTRAIN\u00ae PRRS, HIPRA\uff1bIM\u548cID\uff09\uff0c\u53e6\u4e00\u7a2e\u57fa\u65bcPRRSV2\uff08VR-2332\u682a\uff1bIM\uff09\u2014\u2014\u5728\u65e5\u672cPRRSV2\u967d\u6027\u8fb2\u5834\u4e2d\u7684\u751f\u9577\u8c6c\u96bb\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\u6750\u6599\u8207\u65b9\u6cd5<\/h2>\n<ul>\n<li>V1_IM\u7d44\uff1a\u63a5\u7a2eUNISTRAIN\u00ae PRRS\uff08\u808c\u8089\u6ce8\u5c04\uff09<\/li>\n<li>V1_ID\u7d44\uff1a\u63a5\u7a2eUNISTRAIN\u00ae PRRS\uff08\u76ae\u5167\u6ce8\u5c04\uff09<\/li>\n<li>V2_IM\u7d44\uff1a\u63a5\u7a2eVR-2332\u682a\uff08\u808c\u8089\u6ce8\u5c04\uff09<\/li>\n<\/ul>\n<p>\u6bcf\u6708\u8a55\u4f30\u6240\u6709\u52d5\u7269\u8840\u6db2\u4e2d\u7684PRRSV\u5b58\u5728\uff08RT-PCR\uff09\u548c\u9ad4\u6db2\u53cd\u61c9\uff08CIVTEST\u00ae SUIS PRRS E\/S\u548cA\/S\uff09\u3002\u5728\u63a5\u7a2e\uff083\u9031\u9f61\uff09\u548c\u5c60\u5bb0\uff086\u500b\u6708\u5927\uff09\u4e4b\u9593\uff0c\u8a55\u4f30\u4e86\u8207PRRS\u76f8\u7b26\u7684\u81e8\u5e8a\u75c7\u72c0\u3001\u6297\u751f\u7d20\u7684\u4f7f\u7528\u548c\u5e73\u5747\u65e5\u589e\u91cd\u3002\u6b64\u5916\uff0c\u5728\u6b7b\u4ea1\u52d5\u7269\u4e2d\u6aa2\u67e5\u4e86\u7d44\u7e54\u4e2dPRRSV\u7684\u5b58\u5728\uff08RT-PCR\uff09\u3002\u7d71\u8a08\u5206\u6790\u4f7f\u7528StatsDirect v2.7.7\u9032\u884c\u3002<\/p>\n<div id=\"attachment_26892\" style=\"width: 694px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-26892\" class=\"wp-image-26891 size-full\" src=\"https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/684_229_1.png\" alt=\"\" width=\"684\" height=\"229\" srcset=\"https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/684_229_1.png 684w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/684_229_1-300x100.png 300w\" sizes=\"auto, (max-width: 684px) 100vw, 684px\" \/><p id=\"caption-attachment-26892\" class=\"wp-caption-text\">\u57161 \u2013 \u5be6\u9a57\u7d44\u3002\u4f86\u81eaMiranda\u7b49\uff0c2024\u5e74\u3002<\/p><\/div>\n<p>&nbsp;<\/p>\n<h2>\u7d50\u679c<\/h2>\n<p>\u4e00\u500b\u6708\u5f8c\u672a\u767c\u73fe\u75ab\u82d7\u682a\u5728\u8840\u6db2\u4e2d\uff1b\u7136\u800c\uff0c\u5728\u4e00\u96bb\u6b7b\u4ea1\u52d5\u7269\uff0847 dpv\uff09\u7684\u80ba\u90e8\u767c\u73fe\u4e86PRRSV2MLV\u682a\uff0c\u8a72\u52d5\u7269\u5c6c\u65bcV2_IM\u7d44\u3002<br \/>\n\u572814 dpv\u5f8c\uff0cV1_ID\u7d44\u7684\u81e8\u5e8a\u75c7\u72c0\u5929\u6578\u986f\u8457\u5c11\u65bcV1_IM\u548cV2_IM\u7d44\uff0836 &lt; 74\u548c77\uff0c\u5206\u5225\uff1bp&lt;0.05\uff09\uff0823a\uff09\u3002V1_ID\u7d44\u7684\u55ae\u6b21\u6297\u751f\u7d20\u6ce8\u5c04\u5929\u6578\u7d2f\u8a08\u6700\u4f4e\uff08V1_ID 38\u5929 &lt; V1_IM 87\u5929\u548cV2_IM 84\u5929\uff1bp&lt;0.05\uff09\uff08\u57162b\uff09\u3002<\/p>\n<div id=\"attachment_26900\" style=\"width: 760px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-26900\" class=\"wp-image-26900\" src=\"https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/995_392_1.png\" alt=\"\" width=\"750\" height=\"295\" srcset=\"https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/995_392_1.png 995w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/995_392_1-300x118.png 300w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/995_392_1-768x303.png 768w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/995_392_1-750x295.png 750w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><p id=\"caption-attachment-26900\" class=\"wp-caption-text\">\u57162 &#8211; \u8207PRRSV\u76f8\u5bb9\u7684\u81e8\u5e8a\u75c7\u72c0\u5929\u6578\uff082a\uff09\u548c\u6297\u751f\u7d20\u6cbb\u7642\u61c9\u7528\u5929\u6578\uff082b\uff09\u3002\u6539\u7de8\u81eaMiranda\u7b49\uff0c2024\u5e74\u3002<\/p><\/div>\n<p>\u5728\u63a5\u7a2e\u5f8c\u7684\u7b2c\u4e00\u500b\u6708\uff0cV1_ID\u7d44\u7684\u65e5\u589e\u91cd\u986f\u8457\u9ad8\u65bcV1_IM\u548cV2_IM\u7d44\uff08286.0 &gt; 235.0\u548c234.7\u514b\/\u5929\uff0c\u5206\u5225\uff1bp&lt;0.05\uff09\uff08\u88681\uff09\u3002\u5728\u6240\u6709\u7d44\u4e2d\u5747\u6aa2\u6e2c\u5230PRRSV2\u6297\u9ad4\uff0c\u8868\u660ePRRSV2\u91ce\u5916\u682a\u5728\u5faa\u74b0\u3002<\/p>\n<div id=\"attachment_26909\" style=\"width: 760px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-26909\" class=\"wp-image-26908\" src=\"https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/991_245_1.png\" alt=\"\" width=\"750\" height=\"185\" srcset=\"https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/991_245_1.png 991w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/991_245_1-300x74.png 300w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/991_245_1-768x190.png 768w, https:\/\/prrscontrol.com\/wp-content\/uploads\/2024\/11\/991_245_1-750x185.png 750w\" sizes=\"auto, (max-width: 750px) 100vw, 750px\" \/><p id=\"caption-attachment-26909\" class=\"wp-caption-text\">\u88681 \u2013 \u5e73\u5747\u65e5\u589e\u91cd\uff1aV1_ID\u7d44\u5728\u63a5\u7a2e\u5f8c\u7684\u7b2c\u4e00\u500b\u6708\u589e\u9577\u986f\u8457\u9ad8\u65bc\u5176\u4ed6\u7d44\u3002\u2020 woa \u2013 \u9031\u9f61\u3002\u6539\u7de8\u81eaMiranda\u7b49\uff0c2024\u5e74\u3002<\/p><\/div>\n<p>&nbsp;<\/p>\n<h2>\u8a0e\u8ad6\u8207\u7d50\u8ad6<\/h2>\n<p>\u5118\u7ba1\u5b58\u5728\u57fa\u56e0\u5dee\u7570\uff0cIM PRRSV1_MLV\u548cPRRSV2_MLV\u5728PRRSV2\u967d\u6027\u8fb2\u5834\u4e0a\u63d0\u4f9b\u4e86\u76f8\u4f3c\u7684\u4fdd\u8b77\u3002\u76f8\u53cd\uff0c\u4f7f\u7528ID PRRSV1_MLV\u5247\u53d6\u5f97\u4e86\u66f4\u597d\u7684\u6548\u679c\uff0c\u9019\u8868\u660eID\u75ab\u82d7\u63a5\u7a2e\u662f\u4e00\u7a2e\u6709\u6548\u7684PRRS\u63a7\u5236\u7b56\u7565\u3002\u4f7f\u7528ID\u9014\u5f91\u7684\u5176\u4ed6\u512a\u52e2\u5305\u62ec\u907f\u514d\u91ab\u6e90\u6027\u75c5\u539f\u9ad4\u50b3\u64ad\u548c\u6e1b\u5c11\u58d3\u529b\u53ca\u75bc\u75db\uff083\uff09\u3002<br \/>\n\u9664\u4e86\u65bd\u6253\u9014\u5f91\uff0c\u9019\u4e9b\u767c\u73fe\u53ef\u80fd\u9084\u53ef\u4ee5\u7528\u6240\u6d89\u53ca\u682a\u7684\u514d\u75ab\u5b78\u7279\u6027\u4f86\u89e3\u91cb\uff084\uff09\uff0c\u4ee5\u53ca\u63a5\u7a2e\u6642\u6bcd\u6e90\u6297\u9ad4\u7684\u5e72\u64fe\uff085\uff09\uff0c\u56e0\u70ba\u6bcd\u8c6c\u901a\u5e38\u6703\u63a5\u7a2ePRRSV2\u75ab\u82d7\u3002<\/p>\n<p>\u5982\u679c\u60a8\u60f3\u95b1\u8b80\u66f4\u591a\u95dc\u65bcPRRS\u7684\u51fa\u7248\u7269\uff1a<a href=\"https:\/\/prrscontrol.com\/publications\/\">PRRS Control Publications<\/a><\/p>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\"><strong>\u53c3\u8003\u6587\u737b\uff1a<\/strong><\/p>\n<h6><em>1. Chase-Topping M, Xie J, Pooley C, Trus I, Bonckaert C, Rediger K, Bailey RI, Brown H, Bitsouni V, Barrio MB, Gueguen S, Nauwynck H, Doeschl-Wilson A. New insights about vaccine effectiveness: Impact of attenuated PRRS-strain vaccination on heterologous strain transmission. Vaccine (2020) 23;38(14). <a href=\"https:\/\/doi.org\/10.1016\/j.vaccine.2020.02.015\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/j.vaccine.2020.02.015<\/a><\/em><\/h6>\n<h6>2. Pileri E, Mateu E. Review on the transmission porcine reproductive and respiratory syndrome virus between pigs and farms and impact on vaccination. Vet Research (2016) 28;47(1). <a href=\"https:\/\/doi.org\/10.1186\/s13567-016-0391-4\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1186\/s13567-016-0391-4<\/a><\/h6>\n<h6>3. Miranda J, Romero S, De Lucas L, Saito F, Fenech M, D\u00edaz I. Protection provided by a commercial modified-live porcine reproductive and respiratory syndrome virus (PRRSV) 1 vaccine (PRRSV1-MLV) against a Japanese PRRSV2 field strain. Journal of Veterinary Science (2023) 24(5). <a href=\"https:\/\/doi.org\/10.4142\/jvs.23025\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.4142\/jvs.23025<\/a><\/h6>\n<h6>4. Diaz I, Darwich L, Pappaterra G, Pujols J. Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs. Virology (2006) 351(2):249-59. <a href=\"https:\/\/doi.org\/10.1016\/j.virol.2006.03.046\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1016\/j.virol.2006.03.046<\/a><\/h6>\n<h6>5. Aguirre L, Li Y, Baratelli M, Mart\u00edn-Valls G, Cortey M, Miranda J, Mart\u00edn M, Mateu E. In the presence of non-neutralising maternally derived antibodies, intradermal and intramuscular vaccination with a modified live vaccine against porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) induce similar levels of neutralising antibodies or interferon-gamma secreting cells. Porc Health Manag (2022) 8(1):47. <a href=\"https:\/\/doi.org\/10.1186\/s40813-022-00289-4\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1186\/s40813-022-00289-4<\/a><\/h6>\n<div style=\"text-align:center\" class=\"yasr-auto-insert-visitor\"><\/div>","protected":false},"excerpt":{"rendered":"<p>\u75ab\u82d7\u53ef\u4ee5\u6e1b\u5c11\u8c6c\u7e41\u6b96\u8207\u547c\u5438\u7d9c\u5408\u75c7\u75c5\u6bd2\uff08PRRSV\uff09\u7684\u81e8\u5e8a\u7d50\u679c\u548c\u751f\u7522\u5f71\u97ff\uff0c\u4e26\u63d0\u4f9b\u5169\u7a2e\u65bd\u6253\u9014\u5f91\uff1a\u808c\u8089\u6ce8\u5c04\uff08IM\uff09\u548c\u76ae\u5167\u6ce8\u5c04\uff08ID\uff09\u3002\u6211\u5011\u7684\u76ee\u6a19\u662f\u8a55\u4f30\u5169\u7a2e\u5546\u696dPRRS MLV\u75ab\u82d7\u7684\u6709\u6548\u6027\u2014\u2014\u4e00\u7a2e\u57fa\u65bcPRRSV1\uff08UNISTRAIN\u00ae PRRS, HIPRA\uff1bIM\u548cID\uff09\uff0c\u53e6\u4e00\u7a2e\u57fa\u65bcPRRSV2\uff08VR-2332\u682a\uff1bIM\uff09\u2014\u2014\u5728\u65e5\u672cPRRSV2\u967d\u6027\u8fb2\u5834\u4e2d\u7684\u751f\u9577\u8c6c\u96bb\u3002<\/p>\n","protected":false},"author":18,"featured_media":26303,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_cbd_carousel_blocks":"[]","yasr_overall_rating":0,"yasr_post_is_review":"","yasr_auto_insert_disabled":"","yasr_review_type":"","footnotes":""},"categories":[216],"tags":[220],"class_list":["post-26953","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-216","tag-the-prrs-experts-answer-zh-hant"],"acf":[],"yasr_visitor_votes":{"number_of_votes":0,"sum_votes":0,"stars_attributes":{"read_only":false,"span_bottom":false}},"_links":{"self":[{"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/posts\/26953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/comments?post=26953"}],"version-history":[{"count":3,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/posts\/26953\/revisions"}],"predecessor-version":[{"id":26956,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/posts\/26953\/revisions\/26956"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/media\/26303"}],"wp:attachment":[{"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/media?parent=26953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/categories?post=26953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prrscontrol.com\/zh-hant\/wp-json\/wp\/v2\/tags?post=26953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}