ID&IM administration – PRRSControl

Vaccination of piglets against PRRS: why, when, and how

PRRSControl — Wed, 29 Nov 2023 10:23:30 +0000

Control of the disease caused by the PRRS virus remains a source of frustration for all producers and veterinarians. And no wonder! The reasons why controlling the disease is so complex include the need for a multifactorial approach and the fact that no solution alone is exclusive and effective.

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Can needle-free vaccination help to reduce the use of antibiotics?

PRRSControl — Wed, 15 Nov 2023 08:25:19 +0000

Did you know that needle-free intradermal (ID) vaccination of piglets against the PRRS virus can reduce the use of antibiotics by up to 55% when compared to the intramuscular (IM) use of this vaccine?

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Avoid iatrogenic transmission of African Swine Fever and PRRS virus using Hipradermic®

Dachrit Nilubol — Mon, 05 Sep 2022 09:00:20 +0000

New publication in the International Pig Veterinary Society 2022 Evaluation of ASF and PRRS virus transmission between pigs when using conventional needle and needle-free device Introduction Porcine reproductive and respiratory syndrome (PRRS), a devastating disease in pigs characterized by respiratory and reproductive disease, has been present in Southeast Asia (SEA) since 90’s [1]. In addition to PRRS, the widespread of African swine fever (ASF) in this SEA region has increased a threat to ASF free herds [2]. Intramuscular administration using needles has been the main route of vaccination in pigs although, risks associated with conventional needles are high. PRRS virus (PRRSV), for instance, was transmitted by conventional needles and was able to induce the disease in naïve pigs [3]. Therefore, the objectives of this study were to evaluate African swine fever virus (ASF) and porcine reproductive and respiratory syndrome virus (PRRSV) transmission between conventional needle and needle-free device. Materials and Methods In the present study, forty-two, 3-week-old pigs were procured from a herd free of ASF and PRRSV. The negative statuses against both pathogens were confirmed by PCR in blood samples upon arrival. Eighteen pigs were randomly allocated into 6 groups called seeders of 3 pigs each including […]

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How can we minimize vaccination stress?

Enric Marco — Thu, 26 Aug 2021 08:22:41 +0000

In a PRRS unstable situation, there are occasional outbreaks of late abortions. So, we would like to remove other vaccines before farrowing to minimize the vaccination stress on sows. How can we minimize vaccination stress? Are there any tips to select vaccines with lower vaccination stress? Vaccinating gestating sows during last third of gestation it is always a compromise. When vaccination is done in a PRRS unstable herd it is often one of the reasons for the virus spreading among sows, especially when the needle is not changed for every sow. Therefore, using a needle free device or changing the needle for each sow would be recommended. The main objective of this recommendation is not just to reduce abortions, but even more importantly, to avoid virus circulation, helping achieve a stable PRRS status. But sometimes vaccination can produce abortions even without the presence of PRRS virus. Vaccinations are stressful for the sows and this why any measure to reduce stress will help in reducing abortions. Some recommendations that can help in reducing stress during vaccination include: Vaccinate while sows are distracted with some other event, for example eating time. Vaccinate calmly and slowly. Use narrow and new needles […]

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Can PRRS live vaccine elicit higher and faster immunity through Intradermal vaccination?

Enric Mateu — Wed, 21 Oct 2020 07:42:25 +0000

What kind of immunological benefit can we expect through ID route? The intradermal route is used in many vaccination protocols in humans and animals. The notion behind the use of this route is to take advantage of the excellent antigen presenting capabilities of dermal dendritic cells as well as to reduce the interference created by the presence of maternally-derived antibodies (MDA) in very well irrigated tissues (such as the muscle). In addition, the use of needleless devices for administering the vaccine improves animal welfare. Intramuscular & intradermal vaccination In the case of PRRSV vaccination it has been shown that the intradermal administration is at least equal to the intramuscular administration of live vaccines. In principle, intradermal administration does not result in a faster priming of the immune response. At present, there is no definitive evidence that with PRRSV intradermal vaccination there is less interference with the MDA. If you want to know more about the differences founded between intramuscular and intradermal vaccination, please visit our section Publications. You can ask your own question! Visit Pig333.com and submit your question to the experts. References A. Scollo et al., Livestock Science 233 (2020) 103939. Busquet, M. […]

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PRRS intradermal vaccination of sows: another step forward in the control of PRRS

HIPRA Swine Unit — Tue, 27 Aug 2019 07:52:45 +0000

Numerous strategies have been described for the control of PRRS on farms. After more than 25 years dealing with PRRS disease, most vets agree that in order to successfully control the disease a combination of the following measures is required: animal management, biosecurity, diagnosis and active immunisation. Although vaccination does not necessarily provide full and universal protection against PRRS infection, vaccines have beneficial effects in terms of clinical and virological protection, reducing the impact of the disease. PRRS sow vaccination: What are the benefits? It has been demonstrated that sow vaccination is effective for reduce the number of abortions, the mortality rate of new-born piglets and other reproductive disorders related to PRRS virus infection. On the other hand, with regard to virological parameters, vaccines help to reduce transmission of the infection, since they can contribute to reduce viraemia and shedding. As result, breeding herd vaccination is a useful tool to: Stabilize the herd: thanks to the decrease in the vertical transmission from sows to foetuses. Minimise the impact of an outbreak: due to the homogenization of the sow herd immunity, avoiding negative subpopulations. In this way, there will be fewer opportunities for infection and in the case of infection, […]

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Does intradermal injection of attenuated live PRRSV vaccines offer an immune response as good as intramuscular ones in sows?

Lars Erik Larsen — Thu, 24 May 2018 17:11:50 +0000

Intradermal vaccination have been approved for a number of vaccines including PRRSV MLV. In order for a company to get such a vaccine approved they need to provide detailed information on safety and efficacy. To the best of my knowledge the intradermal vaccination route induce immunity comparable to the intramuscular route. The intradermal route have some positive aspects: no need for needles and by that decrease the risk of transfer of pathogens from pig to pig, less harm to the pig, easier and faster vaccination. My major concern is that it require that the vaccination is performed according to the guideline for the device – i.e. it is important that the device is in close horizontal contact with the skin of the pig at the time of vaccination. The dose volume is typically 10 times less than for the intramuscular vaccination and therefore it is important that the full dose is deposited correct. Thus, you need to give very detailed instructions to the persons that perform the vaccination – when a lot of pigs are to be vaccinated things may go too fast! An idea would be to take blood samples of 10-20 pigs 3 weeks after vaccination and test […]

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