Notes
Cathy Ardies et al. IPVS 2024
This case-report describes the changes on pressure of infection and mortality after the implementation of an intradermal piglet vaccination program against Porcine Reproductive and Respiratory Syndrome (PRRSV), Porcine Circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (Mh) on a commercial pig farm.
Notes
Joel Miranda et al. IPVS 2024
The goal of this study was to evaluate the efficacy of two commercial PRRS MLV vaccines – one based on PRRSV1 (UNISTRAIN® PRRS, HIPRA; IM and ID), and another on PRRSV2 (strain VR-2332; IM) – in growing pigs on a Japanese PRRSV2-positive farm.
Notes
Dachrit Nilubol et al. ESPHM 2023
The objective of this study was to evaluate the iatrogenic transmission of ASF virus and PRRS virus between conventional needles and a needle-free device.
Notes
Kyohyun An et al. APVS 2023
The objectives of this trial were to evaluate if a PRRSV1 vaccine could better control coinfection (PRRSV1 and PRRV2) and the time required to detect NA after vaccination in a site 2 farm in Korea.
Notes
Kyohyun An et al. APVS 2023
The purpose of this trial was to check if the stability of a site 2 in Korea coinfected with PRRSV1 and PRRSV2 was improved by switching from a PRRSV2 vaccine to a PRRSV1 vaccine.
Notes
Adthakorn Madapong et al. Veterinary Microbiology 244 (2020).
The objectives of the present study were to investigate the immune response of pigs vaccinated IM or ID with PRRSV-1 MLV (UNISTRAIN® PRRS). The protective efficacy was evaluated against the challenge with HP-PRRSV-2 (sublineage 8.7/HP-PRRSV-2), either alone or in combination with PRRSV-1 (clade A, subtype 1).
Notes
Laia Aguirre et al. North American PRRS Symposium, 2022.
The objective of the present study was to evaluate the immune response of UNISTRAIN® PRRS administered intradermally or intramuscularlly at 3 or 21 days of age in presence of neutralizing maternally derived antibodies.
Notes
Antoni Dalmau et al. Front. Vet. Sci. 2021
The aim of the present study was to compare intramuscular injection with a needle and intradermic needle-free vaccinations against porcine reproductive and respiratory syndrome (PRRS) in piglets at 28 days old by studying behavioral and physiological reactions.
Notes
Laia Aguirre et al. Porcine Health Manag. 2022 Nov 4
The purpose of this study was to compare the immune response generated by the intramuscular and the intradermal vaccination route against the porcine reproductive and respiratory syndrome virus (PRRSV).
Notes
Dachrit Nilubol et al. IPVS 2022
The objectives of this study were to evaluate African swine fever virus (ASF) and porcine reproductive and respiratory syndrome virus (PRRSV) transmission between pigs when using conventional needles and a needle-free device.
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Laia Aguirre et al. ESPHM 2022
The present study aimed to assess the development of the immune response against PRRSV after vaccination by either the intradermal (ID) or the intramuscular (IM) route in piglets with high MDA levels.
Notes
Dachrit Nilubol et al. ESPHM 2022
The objective of this study was to evaluate ASF and PRRSV transmission with conventional needles and a needle-free device.
Notes
Almudena Sánchez-Matamoros et al. ESPHM 2021
This study analysed whether the Hipradermic® intradermal needle-free device (ID) improves welfare compared to intramuscular injection with a needle (IM) in piglets.
Notes
Almudena Sánchez-Matamoros et al. IPVS 2020
The objective of the present study was to assess thermography as a method of evaluating the inoculation point when vaccinating with the UNISTRAIN® PRRS vaccine in sows using Hipradermic®.
Notes
Almudena Sánchez-Matamoros et al. IPVS 2020
The objective of the present study was to test and compare thermographic vs visual inspection as methods of evaluation of the inoculation point when vaccinating with the UNISTRAIN® PRRS vaccine in piglets using Hipradermic®.
Notes
Ruangurai Kitchodok et al. IPVS 2020
The aim of this study was to evaluate the field behaviour of UNISTRAIN® PRRS MLV vaccine on a PRRSv1 and PRRSv2 co-infected farm with a recent outbreak recorded.
Notes
Ruangurai Kitchodok et al. IPVS 2020
The aim of this study was to evaluate the safety and efficacy of this combination on commercial swine farms in Thailand.
Notes
Fenech, M et al.; ESPHM 2018.
The results obtained allow us to conclude that vaccination of gilts with UNISTRAIN® PRRS ID using a Hipradermic® device enabled the gilts to clear the virus and reduced its vertical and horizontal transmission to piglets.
Notes
Fenech, M et al.; ESPHM 2018.
The results obtained allow us to conclude that a single vaccination of gilts with UNISTRAIN® PRRS ID using a Hipradermic® device is safe and significantly reduced reproductive failure caused by heterologous wild-type PRRS infection during gestation.
Notes
Fenech, M et al.; ESPHM 2018.
Vaccination of gilts with UNISTRAIN® PRRS ID by Hipradermic® improves piglet performance. Moreover, piglets were healthiest during the lactation period and the number of weaned piglets also increased when females were vaccinated with UNISTRAIN® PRRS.
Notes
Busquet, M. et al.; International PRRS Congress 2015.
The obtained results allow us to conclude that the duration of immunity of the UNISTRAIN® PRRS vaccine was achieved 24 weeks after vaccination. In addition, UNISTRAIN® PRRS administered in piglets by the intradermal route with a suitable device had a comparable effect on the fast clearance of the virus to IM administration using a traditional syringe and needle.
Notes
Busquet, M et al.; ESPHM Congress, 2017.
This study confirms that the UNISTRAIN® PRRS and Hipradermic® combination achieved a better user perception based on a lower loss of product (less than 10%) and greater safety than the other combination of a commercial PRRS vaccine and its needle-free device.
Notes
Miranda, J. et al.; ISERPD 2015.
As expected, the variability of IFN-γ-SC responses observed among different strains was not related to the percentage of ORF5 similarity with the vaccine strain. Results demonstrated that the ID administration of UNISTRAIN® PRRS confers higher levels of cell-mediated immune response than using the IM route. This phenomenon suggests that ID route could be considered a candidate to develop future PRRS vaccines.
Notes
Busquet, M. et al.; International PRRS Congress 2015.
The obtained results allow us to conclude that vaccination with UNISTRAIN® PRRS is safe when administered in piglets by the intradermal route with a suitable device according to the recommended vaccination program.
Notes
Busquet, M. et al.; International PRRS Congress 2015.
The obtained results allow us to conclude that UNISTRAIN® PRRS administered ID with a suitable device is effective when administered according to the recommended vaccination program and it is a useful tool to reduce viraemia and the negative clinical and productive consequences of PRRSV
Notes
Busquet, M. et al.; IPVS & ESPHM Congress 2016.
Vaccination with UNISTRAIN® PRRS induces a humoral response in PRRS-naïve pigs regardless of the injection technique used. Both injection techniques had a comparable effect on the antibody response at 28 and 48 dpv, although some higher antibody levels were observed with the ID route.
Notes
Busquet, M. et al.; IPVS & ESPHM Congress 2016.
Vaccination with UNISTRAIN® PRRS induces a humoral response in PRRS-naïve pigs regardless of the injection technique used. Both injection techniques had a comparable effect on the antibody response at 28 and 48 dpv, although some higher antibody levels were observed with the ID route. Vaccination with UNISTRAIN® PRRS ID seems to be a new, safe and immunogenic method for PRRS control plans.
