Notas
Adthakorn Madapong et al. Veterinary Microbiology 244 (2020).
The objectives of the present study were to investigate the immune response of pigs vaccinated IM or ID with PRRSV-1 MLV (UNISTRAIN® PRRS). The protective efficacy was evaluated against the challenge with HP-PRRSV-2 (sublineage 8.7/HP-PRRSV-2), either alone or in combination with PRRSV-1 (clade A, subtype 1).
Notas
Laia Aguirre et al. North American PRRS Symposium, 2022.
The objective of the present study was to evaluate the immune response of UNISTRAIN® PRRS administered intradermally or intramuscularlly at 3 or 21 days of age in presence of neutralizing maternally derived antibodies.
Notas
Antoni Dalmau et al. Front. Vet. Sci. 2021
The aim of the present study was to compare intramuscular injection with a needle and intradermic needle-free vaccinations against porcine reproductive and respiratory syndrome (PRRS) in piglets at 28 days old by studying behavioral and physiological reactions.
Notas
Laia Aguirre et al. Porcine Health Manag. 2022 Nov 4
The purpose of this study was to compare the immune response generated by the intramuscular and the intradermal vaccination route against the porcine reproductive and respiratory syndrome virus (PRRSV).
Notas
Salvador Romero et al. IPVS 2022
The objective of this study was to analyze the combination of an MLV and a KV (SUIPRAVAC® PRRS, HIPRA) to maintain a high level of immunity against PRRSV in sows and to keep producing quality piglets.
Notas
Dachrit Nilubol et al. IPVS 2022
The objectives of this study were to evaluate African swine fever virus (ASF) and porcine reproductive and respiratory syndrome virus (PRRSV) transmission between pigs when using conventional needles and a needle-free device.
Notas
Joel Miranda et al. IPVS 2022
The objective of this study was to analyze the evolution of RT-qPCR results and the type of samples received in Diagnos (HIPRA diagnostic laboratory, Spain) from 2018 to 2021.
Notas
Carles Vilalta et al. IPVS 2022
In the present study, the HIPRA biosecurity scoring tool was re-evaluated, improved, and validated in order to be more precise in detecting biosecurity failures, to be able to compare biosecurity status between pig farms, and prioritize the critical points for improvement.
Notas
Salvador Romero et al. IPVS 2022
The objective of this study was to assess the use of a KV in a combined protocol together with a MLV, evaluating the concentration of neutralizing antibodies in colostrum from sows and the stabilization of the piglets’ PRRSv status on PRRS endemic farms.
Notas
Joel Miranda et al. ESPHM 2022
The objective of this trial was to analyse the performance of a transport liquid for shipping OF samples in a PRRSV monitoring project for gilts.
Notas
Laia Aguirre et al. ESPHM 2022
The present study aimed to assess the development of the immune response against PRRSV after vaccination by either the intradermal (ID) or the intramuscular (IM) route in piglets with high MDA levels.
Notas
Dachrit Nilubol et al. ESPHM 2022
The objective of this study was to evaluate ASF and PRRSV transmission with conventional needles and a needle-free device.
Notas
Lidia de Lucas et al. ESPHM 2022
The objective of this trial was to demonstrate the infection PRRS virus pressure reduction in nurseries owing to a PRRS MLV vaccine applied to piglets in endemically infected farms.
Notas
Arnaud Lebret et al. ESPHM 2022
The aim of the study was to evaluate performances and economic improvements after implementation of such protocol in a farrow-to-finish farm using UNISTRAIN® PRRS.
Notas
Sara Sopena et al. EAVLD 2021
This study aimed at implementing a third-generation sequencing technology for PRRSV as a routine in a private laboratory setting.
Notas
Laura Valls et al. EAVLD 2021
This study aimed at testing an alternative liquid transport media (LTM) for shipping and subsequent detection of the PRRSV on clinical samples by RT-qPCR.
Notas
Almudena Sánchez-Matamoros et al. ESPHM 2021
This study analysed whether the Hipradermic® intradermal needle-free device (ID) improves welfare compared to intramuscular injection with a needle (IM) in piglets.
Notas
Joel Miranda et al. ESPHM 2021
The aim of this study was to establish a systematic monitoring programme for PRRSV in order to classify farms and evaluate the productive and economic impact of PRRSV infection under Dutch field conditions.
Notas
Joel Miranda et al. ESPHM 2021
The aim of this study was to estimate the economic impact of PRRS in the nursery phase depending on the PRRS status at the source farm.
Notas
Juan Hernández García et al. ESPHM 2021
We set out to establish if a recombinant strain that was causing clinical problems could be controlled by a change in vaccine protocol.
Notas
Joel Miranda et al. AASV 2020
The aim of this study was to demonstrate that a PRRSv1 vaccine (UNISTRAIN® PRRS, HIPRA) administered at 2 weeks of age (woa) by ID route can aid in the control of the PRRSv infections in the early nursery phase in European pig farms.
Notas
Emili Barba-Vidal et al. IPVS 2020
This study aims to evaluate the in vitro viability of a PRRSv live attenuated vaccine after its combination with an inactivated vaccine against Glässer disease.
Notas
Almudena Sánchez-Matamoros et al. IPVS 2020
The objective of the present study was to assess thermography as a method of evaluating the inoculation point when vaccinating with the UNISTRAIN® PRRS vaccine in sows using Hipradermic®.
Notas
Almudena Sánchez-Matamoros et al. IPVS 2020
The objective of the present study was to test and compare thermographic vs visual inspection as methods of evaluation of the inoculation point when vaccinating with the UNISTRAIN® PRRS vaccine in piglets using Hipradermic®.
Notas
Ruangurai Kitchodok et al. IPVS 2020
The aim of this study was to evaluate the field behaviour of UNISTRAIN® PRRS MLV vaccine on a PRRSv1 and PRRSv2 co-infected farm with a recent outbreak recorded.
Notas
Daniel Torrents et al. IPVS 2020
The objective of this trial was to analyse how a PRRS positive farm improves its parameters after vaccination of piglets against PRRS.
Notas
Ruangurai Kitchodok et al. IPVS 2020
The aim of this study was to evaluate the safety and efficacy of this combination on commercial swine farms in Thailand.
Notas
Yunn-Huah Yiu et al. IPVS 2020
The purpose of this study was to evaluate the cross-protection efficacy of a commercial PRRS MLV vaccine containing PRRSV1 strain on a Taiwanese swine farm endemically infected with PRRSV2.
Notas
Lidia de Lucas et al. IPVS 2020
The purpose of this study was to evaluate the field efficacy of UNISTRAIN® PRRS (MLV PRRSV1, HIPRA, Spain) against PRRSv2 field infection and to determine whether there were differences in terms of piglet performance between UNISTRAIN®PRRS and a commercial MLV PRRSv2 vaccine.
Notas
Cheong Yeotaek et al. IPVS 2020
Vaccination with MLV vaccines has been reported to achieve farm stabilisation more quickly than other methods. This is a case report of a clinical outbreak on a negative farm in Korea.
Notas
Torrents, D., Miranda, J., Pedrazuela, R. et al. Porcine Health Management 5, 26, 2019.
Implementation of PRRSV status classification system in swine breeding herds from a large integrated group in Spain.
Notas
Ruangurai Kitchodok et al.; Asian Pig Veterinary Society Congress, 2019
Under PRRSV2 field infection in 4 Thai farms, piglets vaccinated with UNISTRAIN® PRRS showed a significant improvement in productivity compared with the unsuccessful outcome achieved with the previous PRRSV2 vaccine.
Notas
Ruangurai Kitchodok et al.; Asian Pig Veterinary Society Congress, 2019
In this study UNISTRAIN® PRRS was shown to be safe and effective in gilts, sows and piglets controlling PRRSV2 clinical problems in 16 Thai swine farms.
Notas
Miranda, J et al.; Asian Pig Veterinary Society Congress, 2019
This study shows how UNISTRAIN® PRRS contributes in controlling reproductive disorders on a Taiwanese farm affected by PRRSV1 and PRRSV2.
Notas
Yunn-Huah Yiu et al.; Asian Pig Veterinary Society Congress, 2019
In the same production system, the heterologous protection conferred by UNISTRAIN® PRRS against PRRSV2 infection was more effective compared with the outcome achieved with the previous PRRSV2 vaccine.
Notas
Torrents, D et al.; AASV (American Association of Swine Veterinarians) Annual Meeting, 2019
These results provide better understanding of the productive impact of European PRRSV circulation in breeding farms, reinforcing the efforts to stabilize and maintain stable the PRRS-positive farms, especially in high-density swine production areas where elimination of PRRS virus is costly and of low risk of long-term success.
Notas
Sánchez-Matamoros, A. et al.; Porcine Health Management (2019) 5:11
https://doi.org/10.1186/s40813-019-0118-9
The aim of this study was to evaluate the safety and long-term immunity of the authorized combined administration of a PRRSV MLV vaccine and an inactivated vaccine against porcine parvovirus and Erysipelothrix rhusiopathiae simultaneously used.
Notas
Miranda, J. et al.; ESPHM Congress 2019.
This study was conducted to test the efficacy of UNISTRAIN® PRRS when administered intramuscularly or intradermally in pigs against a challenge with a PRRSV2 and a challenge with co-infection with PRRSV2 and PRRSV1.
Notas
Miranda, J. et al.; ESPHM Congress 2019.
The aim of this study was to assess the dynamics of homologous neutralizing antibodies (NA) against the PRRSV MLV vaccine strain during this immunization schedule are presented.
Notas
Torrents, D et al.; ESPHM Congress 2019.
The aim of this study was to evaluate the economic benefits of achieving PRRS stability in PRRS positive unstable breeding herds due to the improvement of the number of weaned piglets.
Notas
Torrents, D. et al.; ESPHM Congress 2019.
The aim of this study was to assess the effect of SMV with UNISTRAIN® PRRS on the likelihood of changing a PRRS stable status classification of breeding herds.
Notas
Torrents, D. et al.; ESPHM Congress 2019.
The aim of this study was to assess the impact of SMV with UNISTRAIN® PRRS on the productive performance of PRRS stable breeding herds.
Notas
Valls, L. et al.; ESPHM Congress 2019.
The aim of this study is to report on the way to overcome some of the practical limitations of PRRSV ORF5 sequencing in a diagnostic laboratory.
Notas
Seo, S.W. et al.; IPVS 2018.
When PRRSV enters in a breeding farm, UNISTRAIN®PRRS mass vaccination can be a safe and efficacious method to homogenize sow immune status and produce PRRS-negative piglets.
Notas
Seo, S.W. et al.; IPVS 2018.
In overall, piglet vaccination with UNISTRAIN®PRRS improves productivity especially in farms co-infected with type 1 and 2 PRRSV.
Notas
Simon-Grifé, M. et al.; IPVS 2018.
It was demonstrated that the association of UNISTRAIN® PRRS and AUSKIPRA® GN administered by the intradermal and the intramuscular routes is as safe and efficacious as the administration of both products separately.
Notas
Miranda, J et al.; IPVS 2018.
The results of this study suggest that both PRRSV recirculation and lateral infections can play a critical role for the control of PRRS in sow´s farms. So, internal and external biosecurity are both key points in the PRRSV control strategies.
Notas
Torrents, D et al.; AASV 2018.
We have established for the first time in Spain the bases for a systematic PRRS monitoring protocol in accordance with the current US standards.
Notas
Schyns, M et al.; ESPHM 2018.
In this study, serum profiling was used to gain insight in the course of a PRRS infection at a farm with complaints. It showed that the vaccination strategy should be changed.
Notas
De Lucas, L et al.; IPVS 2018.
The safety of the combined administration of UNISTRAIN® PRRS and GRIPORK® is confirmed with regard to all the evaluated parameters (local and systemic reactions, rectal temperature and sow reproductive performance).
Notas
Martínez, C. et al.; APVS 2015.
These results suggest there is no interference on PRRSv viability between vaccine components when UNISTRAIN® PRRS is reconstituted with GRIPORK®.
Notas
Fenech, M et al.; ESPHM 2018.
The results obtained allow us to conclude that vaccination of gilts with UNISTRAIN® PRRS ID using a Hipradermic® device enabled the gilts to clear the virus and reduced its vertical and horizontal transmission to piglets.
Notas
Fenech, M et al.; ESPHM 2018.
The results obtained allow us to conclude that a single vaccination of gilts with UNISTRAIN® PRRS ID using a Hipradermic® device is safe and significantly reduced reproductive failure caused by heterologous wild-type PRRS infection during gestation.
Notas
Fenech, M et al.; ESPHM 2018.
Vaccination of gilts with UNISTRAIN® PRRS ID by Hipradermic® improves piglet performance. Moreover, piglets were healthiest during the lactation period and the number of weaned piglets also increased when females were vaccinated with UNISTRAIN® PRRS.
Notas
Lyoo, S et al.; Veterinary Immunology and Immunopathology 2016.
Although this experiment was performed against only one type2 PRRSV isolate, VP-046, MLV vaccine showed a certain degree of efficacy against hetero-genotype PRRSV in the early course of infection.
Notas
Roca, M et al.; The veterinary journal. 2011.
Immunisation with a genotype I attenuated PRRSV vaccine provided partial protection against challenge with a highly virulent genotype II strain.
Notas
Niemann, O. et al.; IPVS 2014.
The results may be indicative of a decrease in the infection pressure exerted by PRRSV in the nursery as a consequence of the active vaccination of the sows. Nevertheless, it was not possible to eradicate the infection from the herd, but the productive parameters show clinical and virological stabilization of the breeding herd and the nursery.
Notas
Niemann, O. et al.; IPVS 2014.
After the change of vaccine the reproduction data of the farm improved. No side effects occurred and the production was successfully stabilized. Nevertheless the transmission of PRRSV from sows to piglets couldn`t be found the nursery remained PRRSV positive and showed clinical signs of PRDC. A full clinical stabilisation would require a piglet vaccination.
Notas
Miranda, J. et al.; ESPHM 2015.
When discussing about PRRS vaccine strain efficacy, one of the most important challenges for any vaccine strain is their ability to confer heterologous protection in front of arrival of new field strains.. The present study is a good example to demonstrated that in front the same field challenge, the strain contained into UNISTRAIN® PRRS confers better heterologous protections than another EU strain MLV vaccine.
Notas
Miranda, J. et al.; International PRRS Congress 2015.
Vaccination with UNISTRAIN® PRRS significantly reduced the clinical respiratory signs associated with PRRS and the percentage of antibiotic treatments. Moreover, vaccination reduced the percentage of animals with lung lesions and positive to PRRSv.
Notas
Miranda, J. et al.; International PRRS Congress 2015.
Vaccination with UNISTRAIN® PRRS was demonstrated to be a useful tool to reduce mortality, animals with lung lesions positive to PRRSV, number of viraemic animals and the percentage of animals treated with antibiotics on farms with a previous history of PRRS outbreaks.
Notas
Camprodon, A. et al.; ESPHM 2015.
The safety of the combined administration of ERYSENG® PARVO and UNISTRAIN® PRRS is confirmed with regard to all the evaluated parameters (local reactions, general clinical signs and body temperature). The combined administration of ERYSENG® PARVO and UNISTRAIN® PRRS did not have any negative effects on the reproductive and farrowing parameters.
Notas
Camprodon, A. et al.; ESPHM 2015.
Vaccination with the combination of ERYSENG® PARVO and UNISTRAIN® PRRS effectively protects animals from transplacental infection caused by PPV.
Notas
Camprodon, A. et al.; ESPHM 2015.
The humoral immunity elicited by the combined administration of ERYSENG® PARVO and UNISTRAIN® PRRS enabled animals to manage the experimental infection, showing a reduction in fever and skin lesions after a challenge with virulent E. rhusiopathiae strains.
Notas
Miranda, J. et al.; ESPHM 2015.
Vaccination with the combined administration of ERYSENG® PARVO and UNISTRAIN® PRRS significantly reduced the percentage of viraemic gilts and the duration of viraemia in gilts after a heterologous PRRS infection. Also, the combined use of the vaccines reduced vertical and horizontal transmission to their piglets. The results obtained allow the conclusion to be drawn that the efficacy in terms of viraemia after a PRRS challenge with the combined use of the two vaccines is comparable to that of UNISTRAIN® PRRS administered alone.
Notas
Miranda, J. et al.; ESPHM 2015.
After gilt infection, piglets from the vaccinated gilts were heavier when weaned and grew faster than piglets from the control gilts. Overall piglet performance was significantly better in piglets born from vaccinated gilts with the combined administration of ERYSENG® PARVO and UNISTRAIN®PRRS.
Notas
Miranda, J. et al.; ESPHM 2015.
The combined administration of ERYSENG® PARVO and UNISTRAIN® PRRS significantly reduced the number of weak piglets and the presence of mummies in vaccinated gilts after a heterologous PRRSv challenge. So the use of the vaccine mixture clinically protected gilts from a heterologous PRRSv infection. The results obtained allow the conclusion to be drawn, that efficacy in terms of clinical protection after a PRRS challenge with the combined use of the two vaccines is comparable to that of UNISTRAIN® PRRS administered alone.
Notas
Miranda, J. et al.; IPVS & ESPHM Congress 2016.
The results of the study demonstrated that the viability of the PRRS virus after mixing UNISTRAIN®PRRS and ERYSENG® PARVO can be guaranteed for 2 hours after reconstitution, unlike the non-registered combination of the other commercial MLV combined with the SE and PPV vaccine from the same manufacturer.
Notas
Miranda, J. et al.; IPVS & ESPHM Congress 2016.
Results of the present study suggest that UNISTRAIN® PRRS administered alone or combined with ERYSENG® PARVO induces a significant specific CMI response against heterologous PRRSV strains after a common vaccination scheme with primary vaccination and revaccination 4 months later.
Notas
Busquet, M. et al.; International PRRS Congress 2015.
The obtained results allow us to conclude that the duration of immunity of the UNISTRAIN® PRRS vaccine was achieved 24 weeks after vaccination. In addition, UNISTRAIN® PRRS administered in piglets by the intradermal route with a suitable device had a comparable effect on the fast clearance of the virus to IM administration using a traditional syringe and needle.
Notas
Busquet, M et al.; ESPHM Congress, 2017.
This study confirms that the UNISTRAIN® PRRS and Hipradermic® combination achieved a better user perception based on a lower loss of product (less than 10%) and greater safety than the other combination of a commercial PRRS vaccine and its needle-free device.
Notas
Miranda, J. et al.; ISERPD 2015.
As expected, the variability of IFN-γ-SC responses observed among different strains was not related to the percentage of ORF5 similarity with the vaccine strain. Results demonstrated that the ID administration of UNISTRAIN® PRRS confers higher levels of cell-mediated immune response than using the IM route. This phenomenon suggests that ID route could be considered a candidate to develop future PRRS vaccines.
Notas
Busquet, M. et al.; International PRRS Congress 2015.
The obtained results allow us to conclude that vaccination with UNISTRAIN® PRRS is safe when administered in piglets by the intradermal route with a suitable device according to the recommended vaccination program.
Notas
Busquet, M. et al.; International PRRS Congress 2015.
The obtained results allow us to conclude that UNISTRAIN® PRRS administered ID with a suitable device is effective when administered according to the recommended vaccination program and it is a useful tool to reduce viraemia and the negative clinical and productive consequences of PRRSV
Notas
Busquet, M. et al.; IPVS & ESPHM Congress 2016.
Vaccination with UNISTRAIN® PRRS induces a humoral response in PRRS-naïve pigs regardless of the injection technique used. Both injection techniques had a comparable effect on the antibody response at 28 and 48 dpv, although some higher antibody levels were observed with the ID route.
Notas
Busquet, M. et al.; IPVS & ESPHM Congress 2016.
Vaccination with UNISTRAIN® PRRS induces a humoral response in PRRS-naïve pigs regardless of the injection technique used. Both injection techniques had a comparable effect on the antibody response at 28 and 48 dpv, although some higher antibody levels were observed with the ID route. Vaccination with UNISTRAIN® PRRS ID seems to be a new, safe and immunogenic method for PRRS control plans.
Notas
Miranda, J. et al.; International PRRS Congress 2015.
Vaccination with UNISTRAIN® PRRS significantly reduced the viral load in sera, the number of viraemic piglets and the length of the viraemia after a heterologous PRRS challenge with a pathogenic UK strain.
Notas
Miranda, J. et al.; International PRRS Congress 2015.
Vaccination with UNISTRAIN® PRRS significantly reduced the viral load in sera, the number of viraemic piglets and the length of the viraemia after a heterologous PRRS challenge with a pathogenic Spanish strain.
Notas
Bonckaert, C. et al.; International PRRS Congress 2015.
The results of the study demonstrate that vaccination with UNISTRAIN® PRRS provides a partial virological protection against challenge with the East European subtype 3 PRRSv strain Lena.
Notas
Miranda, J. et al.; IPVS 2014.
Genetic/antigenic diversity and variability in the immunobiological properties of the PRRSV (3,4) may compromise the heterologous protection generated by vaccination in PRRS control strategies. Although PRRS immunity is not yet fully understood, the significance not only of the NA but the cell-mediated immunity is important for a better understanding of vaccine performance (3). The present study showed that primo-immunization of naïve gilts with UNISTRAIN® PRRS induced a significant specific cell-mediated immunity against 5 heterologous PRRSV strains.
Notas
Fenech, M. et al.; ESPHM 2013.
Vaccination of gilts with UNISTRAIN® PRRS allowed piglets born from PRRSV infected gilts to survive and clearly perform better during lactation period.
Notas
Fenech, M., et al.; ESPHM 2013.
Vaccination of sows with UNISTRAIN® PRRS allowed piglets born from PRRSV infected sows to survive and clearly perform better during lactation period.
Notas
Fenech, M. et al.; ESPHM 2013.
Vaccination with UNISTRAIN® PRRS significantly reduced reproductive failure caused by wild-type infection during gestation.
Notas
Fenech, M. et al.; ESPHM 2013.
Vaccination with UNISTRAIN® PRRS enabled gestating sows to clear the virus and reduced its vertical and horizontal transmission to foetuses. There was a reduction of shedding and infection pressure.
Notas
Fenech, M. et al.; ESPHM 2013.
Vaccination with UNISTRAIN® PRRS significantly reduced reproductive failure caused by wild-type infection during gestation. After vaccine administration there was not any adverse effect derived from vaccination. No abortion occurred in any vaccinated sow (100% farrowing rate).
Notas
Fenech, M. et al.; ESPHM 2013.
Vaccination with UNISTRAIN® PRRS significantly reduced reproductive failure caused by wild-type infection during gestation. After vaccine administration there was not any adverse effect derived from vaccination. No abortion occurred in any vaccinated sow (100% farrowing rate).
Notas
Bonckaert, C. et al.; Porcine Health Management Journal 2016.
This study concludes that vaccination of pigs with the modified-live vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection against the PRRSV subtype 3 strain Lena.
Notas
Young, S.L. et al.; APVS Congress 2017.
This study confirms that UNISTRAIN® PRRS vaccine could effectively control reproductive failures induced by PRRSV through increased ratio of live born to total born piglets and decreased mortality rate of suckling piglets.
Todos los derechos reservados. © HIPRA
